A recent article titled “Recent Progress and Advancement in Detecting Methylmercury Using a Battery of Biosensors and Biomolecular-Based Techniques: An Updated Overview,” published in TrAC Trends in Analytical Chemistry, provides a comprehensive analysis of the latest advancements in biosensor technologies for detecting methylmercury (MeHg), the most toxic form of mercury.

Authored by A.F.P. Allwin Mabes Raj, Raghuraj Singh Chouhan, Aljoša Košak, Milena Horvat, Aleksandra Lobnik, Tomaž Rijavec, and Aleš Lapanje, the review critically evaluates the performance of various biosensor platforms, considering key parameters such as sensitivity, selectivity, response time, and adaptability. The study highlights recent technological innovations that have enhanced MeHg detection’s effectiveness while identifying existing challenges and potential improvements for future research.

A key focus of the article is the need for improved in situ detection methods, particularly for biomedical and environmental monitoring applications. The review discusses how advancements in biosensor design could contribute to real-time detection in aqueous environments, addressing critical limitations of current technologies. The authors emphasize the importance of developing more efficient, cost-effective, and reliable biosensors to facilitate broader applications in scientific research and practical field use.

By providing an updated perspective on state-of-the-art MeHg detection, this study offers valuable insights into the ongoing efforts to enhance biosensor technologies and underscores the significance of continued innovation in this critical area of analytical chemistry.

📖 [https://doi.org/10.1016/j.trac.2025.118157]

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GMOS Train project coordinator
prof. dr. Milena Horvat, Ph.D.
Head of Department of Environmental Sciences, Jožef Stefan Institute

+386 1 5885 389
info@gmos.si

This project will receive funding from the European Union’s Horizon 2020 research and innovation programme under the Marie Sklodowska-Curie grant agreement no. 860497.

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